Search results for "Disease process"
showing 8 items of 8 documents
Shifts in gut microbiota composition in an APP/PSS1 transgenic mouse model of Alzheimer's disease during lifespan.
2017
Alzheimer's disease (AD) is the most common form of dementia and one of the major causes of disability and dependency in older people. Accumulating evidences link gut microbiota with different diseases and its relationship with neurodegenerative diseases is becoming most intriguing. This study was aimed to compare the gut microbiota of transgenic APP/PS1 (TG) mice, a well‐established deterministic mouse model of AD, with their C57BL/6 wild‐type (WT) littermates. Faecal samples were collected from 3‐, 6‐ and 24‐month‐old mice and analysed by pyrosequencing of the V1–V3 region of the bacterial 16S rRNA genes. Bacterial profiles were similar in all young mice (3 months old), and started to div…
Volatile organic compounds fingerprint of Alzheimer’s disease.
2015
Alzheimer's disease (AD) is a profoundly life changing condition and once diagnosis occurs, this is typically at a relatively late stage into the disease process. Therefore, a shift to earlier diagnosis, which means several decades before the onset of the typical manifestation of the disease, will be an important step forward for the patient. A promising diagnostic and screening tool to answer this purpose is represented by breath and exhaled volatile organic compounds (VOCs) analysis. In fact, human exhaled breath contains several thousand of VOCs that vary in abundance and number in correlation with the physiological status. The exhaled VOCs reflect the metabolism, including the neuronal …
La relación medico-paciente ¿un vínculo distinto o distante?
2008
The goal of this paper is to show aspects in the physician-patient interaction that play an important role in the disease process. It is located in relation to communication process, clinical decision-making, and the style and perceptions usually experienced by the patients.
Psicología y Salud. Calidoscopio de Prácticas Diversas
2006
The paper establishes the developments and aims of Health Psychology as a specialized field of the psychological science. Its origins and definition are described, as well as its conceptual contributions with regard to the psychological factors that mediate in the health – disease process. The physician – patient relation is characterized and it is located in relation to interdisciplinary and work in a hospital institution. It analyses the psychologist’s role and the interventions to promote and increase health; to prevent, assess and treat / rehabilitate specific disorders; analyze and improve the system and sanitarian attention; train professionals and research.
Role of fungus in eosinophilic sinusitis.
2005
Chronic rhinosinusitis is characterized by a broad diagnostic and etiologic spectrum. It has been postulated that fungal organisms might represent the immunologic target initiating and maintaining the disease process in patients with chronic rhinosinusitis as a common denominator. This review analyzes the available data to describe the current understanding of the role of fungus in the pathophysiology of chronic rhinosinusitis.Recent findings have demonstrated that using highly sensitive methods, the detection rate of fungi in nasal mucin can be increased to approximately 100% in patients and in healthy controls. If this ubiquitous fungal contamination were to be related to a causative mech…
Eustachian tube dysfunction in OSMF- often present seldom discovered
2014
Objectives: To evaluate the effect of OSMF on the eustachian tube function and to correlate it with various grades of the disease. Study Design: Twenty OSMF patients (40 ears) and 20 healthy controls (40 ears) were evaluated for eustachian tube function by eustachian tube function test, tympanometry and audiometry. Results: The audiometric and tympanometric analysis showed no significant differences in hearing abilities of OSMF patients and controls and between various grades of OSMF, indicating no hearing impairment. However, eustachian tube function test revealed a statistically significant difference in eustachian tube function in OSMF patients and controls. Further, there was a signific…
Severe Chronic Allergic (and Related) Diseases: A Uniform Approach – A MeDALL – GA<sup>2</sup>LEN – ARIA Position Paper
2012
Concepts of disease severity, activity, control and responsiveness to treatment are linked but different. Severity refers to the loss of function of the organs induced by the disease process or to the occurrence of severe acute exacerbations. Severity may vary over time and needs regular follow-up. Control is the degree to which therapy goals are currently met. These concepts have evolved over time for asthma in guidelines, task forces or consensus meetings. The aim of this paper is to generalize the approach of the uniform definition of severe asthma presented to WHO for chronic allergic and associated diseases (rhinitis, chronic rhinosinusitis, chronic urticaria and atopic dermatitis) in …
Occupational Diseases: Asbestosis and Mesothelioma in Forensic Practice
2019
Diagnosis of occupational diseases, a strong collaboration between radiologic and clinical features with related occupational history and literature supporting, and an association between the exposure and the disease process are requested. Further pathological findings emerging at biopsy or autopsy, which are considered ancillary examination techniques, may assist in the judgment related to causal chain reconstruction.